Dr. Richard Wassenaar

Adjunct Research Professor
Best Theranostics Ltd à Nordion
447 March Rd
Kanata ON, K2K 1X8
Tel: 
(613) 592-3400 Ext. 2539
Email: 
richard [dot] wassenaaratnordion [dot] com

Research Summary

Congestive heart failure (CHF) is a major problem in Canada. Approximately 30000 to 40000 Canadians with CHF suffer from dyssynchronous cardiac contraction, that is, the ventricles of the heart are beating out of phase, leading to inefficient pumping. Phase analysis of SPECT blood pool imaging may potentially provide a means of quantify cardiac contraction and allow cardiologists to better manage patients. Work in our lab is focused developing phase analysis for clinical use. Challenges associated with accurate and reproducible phase analysis include fitting of the data to physiological models, sampling of the myocardial wall, and edge detection to delineate the chambers of the heart.

Assessment of lung perfusion using combined SPECT/CT, including delineation of the lobes of the lung on the CT, and more accurate image co-registration techniques for fusion of the SPECT and CT images.

PET research including novel tracers such as 18-F-FLT for cardiac applications, 11-C-acetate for prostate imaging, and 82-Rb for measurement of tumor perfusion.

Publications/Presentations

  • H.K. Tan, R.W. Wassenaar and W. Zeng, “Collimator Selection, Acquisition Speed and Visual Assessment of Bexxar Biodistribution in a Phantom Model”, J Nucl Med Technol, 34(4), 224-7(2006).
  • B. Dej, R. Wassenaar, "Quantifying Phase Analysis Parameters for Normal Cardiac Synchrony," IEEE Nuclear Science Symposium Conference Record, 5, 3180-3184 (2006).
  • R. Wassenaar and R. deKemp, “Detector Quality Assurance Using 137-Cs Singles Transmission Imaging”, IEEE Trans Nuc Sci, 53, 108-112 (2006).
  • R. Wassenaar and R. deKemp, “Characterization of PET Partial Volume Corrections for Variable Myocardial Wall Thicknesses”, IEEE Trans Nuc Sci, 53,175-180 (2006).
  • J. Renaud M. Lortie, R. Wassenaar, J. DaSilva, R.S. Beanlands and R.A. deKemp, “Quantifying the Normal Range of Myocardial Blood Flow with 13N-Ammonia PET and Tracer Kinetic Modeling”, IEEE Nuclear Science Symposium Conference Record, 3,1686-1690 (2005).
  • R. Wassenaar and R. deKemp, “An Extravascular Density Model for PET Partial Volume Correction”, IEEE Nuclear Science Symposium Conference Record, 3,1809-1813 (2005).